I am Associate Professor in the department of Health Technology & Services Research (HTSR), University of Twente, The Netherlands. I hold a MSc in Technical Computer Science and obtained my PhD in the field of Health Technology Assessment (2008). I worked at the University Medical Centre Utrecht, The Netherlands, from 2004-2015 before joining HTSR in 2015.
My research interests relate to the use of simulation models to assess the expected impact of innovations in healthcare, with a focus on the evaluation and optimization of using novel diagnostic tests in oncology and cardiovascular disease. In this context I use patient-level simulation models to reflect patient heterogeneity, metamodeling methods to optimize target outcomes, and value of information analysis to inform decision making. In the context of early health technology assessment, I am interested in applying minimal modeling value of information approaches to support research prioritization decisions. I am currently a member of the ISPOR Task Force on Emerging Good Practices for Value of Information analysis.